Ion Chromatography Standards
Apexbio Technology LLC L-α-Aminoadipic Acid 1118-90-7 1g
L-alpha-Aminoadipic Acid (1118-90-7) is a small-molecule inhibitor targeting glutamine synthetase It is designed to competitively inhibit glutamine synthetase activity thereby modulating glutamate metabolism and neurotransmission pathways L-alpha-Aminoadipic Acid exerts its biological activity primarily through stereospecific competitive inhibition of glutamine synthetase In in vitro studies L-alpha-Aminoadipic Acid impacts astrocytic function preceding its gliotoxic effects and modulates kynurenic acid production in hippocampal tissues Based on these pharmacological properties L-alpha-Aminoadipic Acid holds research potential in the investigation of astrocyte function and neurological metabolism within neuroscience and pharmacology fields
AccuStandard, Inc BROMIDE 100ML
Anion Standard - Bromide. 100 mL. 1000 ?g/mL in 2% Sodium hydroxide.
Apexbio Technology LLC Minoxidil 38304-91-5 1g
Minoxidil (CAS 38304-91-5) is a synthetic pyrimidine derivative that functions as a direct-acting vasodilator It exerts its pharmacological effects by opening ATP-sensitive potassium channels in vascular smooth muscle cells leading to membrane hyperpolarization and subsequent relaxation of arterial smooth muscle These actions result in reduced peripheral vascular resistance and lower blood pressure Minoxidil is widely utilized in biomedical research to investigate mechanisms of vasodilation vascular smooth muscle physiology and the role of potassium channels in cardiovascular regulation
Apexbio Technology LLC Perindopril 82834-16-0 1g
Perindopril (CAS 82834-16-0) is an inhibitor of angiotensin I-converting enzyme (ACE) widely used in biomedical research By blocking ACE activity Perindopril suppresses the formation of angiotensin II a peptide involved in vasoconstriction and angiogenesis In cancer studies Perindopril has demonstrated the ability to inhibit tumor growth and angiogenesis in head and neck squamous cell carcinoma models While it does not significantly affect cell proliferation in vitro it reduces VEGF mRNA expression and promoter activity at concentrations as low as 1 M In vivo Perindopril has been shown to suppress tumor growth and lower blood pressure without altering heart rate supporting its application in oncology and cardiovascular research
Apexbio Technology LLC Fluocinonide 356-12-7 1g
Fluocinonide (CAS 356-12-7) is a synthetic glucocorticoid steroid targeting intracellular glucocorticoid receptors (GR) It is designed to modulate gene transcriptional activity thereby regulating the production and release of inflammatory cytokines and mediators in the inflammatory response pathway Fluocinonide exerts its biological activity primarily through binding to glucocorticoid receptors and forming receptor-ligand complexes which influence cellular and molecular inflammatory signaling cascades Based on these pharmacological properties fluocinonide holds research potential in studying pathophysiological mechanisms of inflammatory skin conditions evaluating topical corticosteroid metabolism and absorption and facilitating investigations focused on dermatological inflammatory responses
Waters Corp WATERS CORPORATION Ion Calibration Standard, Bromate, 1000 mg/L, 125 mL
This is a 125 mL liquid standard containing Bromate at a concentration of 1000 mg/L in H2O. It can be used for primary calibration or to prepare second source calibration check standards. This certified reference material is traceable to NIST Standard Reference Materials and is covered by ISO 17034 accreditation.
- Liquid formulation in H2O, 125 mL volume
- Bromate concentration: 1000 mg/L
- For environmental applications and primary/secondary calibration
- Traceable to NIST SRMs, guaranteed stable for one year
- ISO 17034 accredited CRM
- Supports methods EPA 300.0, EPA 300.1, SM 4110 B
- Store at 4 ± 2°C
- Shelf life: 24 months from manufacture (12 months min. on ship)
- Hazardous material; special freight/charges may apply
Inorganic Ventures 1000µg/mL POTASSIUM 125mL
Matrix: Nitric Acid (HNO3), Starting Material: KNO3, Analyte: I- 1000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
Apexbio Technology LLC L-Phenylephrine 59-42-7 1g
L-Phenylephrine (CAS 59-42-7) is a selective agonist of the adrenergic 1A receptor exhibiting a Ki of 1 4 M with markedly lower affinity for 1B (Ki 23 9 M) and 1C (Ki 47 8 M) subtypes In vitro L-Phenylephrine has been shown to reduce apoptosis in neonatal rat cardiomyocytes following hypoxia and serum deprivation and to stimulate proliferation in neural progenitor cells It also increases the cross-sectional area and modulates gene expression in rat neonatal cardiomyocytes In vivo local administration in rats induces cutaneous anesthesia through 1-adrenergic receptor activation and clinical data suggest oral administration reduces nasal airway resistance These properties make L-Phenylephrine a valuable tool for studying 1A-adrenergic receptor-mediated cellular responses
Apexbio Technology LLC Diuron 330-54-1 1g
Diuron is a small-molecule inhibitor targeting electron transport within chloroplasts It is designed to interfere with photosynthesis by suppressing electron transfer thereby affecting cellular energy metabolism via reduced ATP and NADH synthesis Diuron exerts its biological activity primarily through inhibition of electron transfer in chloroplasts In experimental studies in animal models dietary administration of Diuron at elevated concentrations is associated with increased occurrence of urothelial carcinoma Based on these pharmacological properties Diuron holds research potential in studies of photosynthetic biochemical pathways cellular energy regulation and chemical-induced carcinogenesis
Thermo Scientific Dionex™ Retention Time Standards for Ion Chromatography
For Use With Routine Anion Determinations | Type: Standard | Standard Components Fluoride 2 mg/L, Chloride 24 mg/L, Nitrite 16 mg/L, Bromide 36 mg/L, Nitrate36 mg/L, Phosphate 26 mg/L, Sulfate 40 mg/L | Volume (Metric) 50 mL
Apexbio Technology LLC Aliskiren 173334-57-1 1g
Aliskiren (CAS 173334-57-1) is a small-molecule inhibitor that targets human renin an aspartyl protease involved in the regulation of the renin angiotensin aldosterone system (RAAS) By directly inhibiting renin activity Aliskiren suppresses the conversion of angiotensinogen to angiotensin I thereby modulating downstream effects on blood pressure regulation It is clinically approved for the management of essential hypertension In biomedical research Aliskiren serves as a tool compound to investigate RAAS-mediated pathways and the physiological consequences of direct renin inhibition in cardiovascular renal and metabolic disease models
Apexbio Technology LLC Ibuprofen 15687-27-1 1g
Ibuprofen (CAS 15687-27-1) is a small-molecule inhibitor targeting cyclooxygenase enzymes COX-1 and COX-2 It is designed to inhibit prostaglandin prostacyclin and thromboxane biosynthesis thereby regulating inflammation and pain pathways Ibuprofen exerts its biological activity primarily through COX enzyme inhibition In cell-based studies ibuprofen demonstrates anti-proliferative activity with an IC50 value of approximately 12 M for COX-1 and 80 M for COX-2 in relevant experimental models including human colon carcinoma HCT-116 cells Based on these pharmacological properties ibuprofen holds research potential in inflammation studies oncology lipid metabolism and neurobiology
Apexbio Technology LLC XTT CELL PROLIF KIT-1000mg
The XTT Cell Proliferation Assay Kit is a crucial tool in biomedical research used to assess cell viability and proliferation in various studies Originating from colorimetric assays it measures the activity of mitochondrial enzymes that reduce the tetrazolium compound XTT to a colored formazan product indicating metabolically active cells This assay is commonly used in in vitro settings for drug screening and evaluating cytotoxicity in cell lines It shows activity in the nanomolar to low micromolar range depending on cell type and conditions Typical applications include testing cancer cell models evaluating potential therapeutic agents and conducting high-throughput screening due to its non-radioactive and sensitive nature Experimental concentrations typically depend on the specific research design allowing for flexibility and precision in diverse experimental setups
Inorganic Ventures 10 000µg/mL CHLORIDE 125mL
Matrix: Water (H2O), Starting Material: KCl, Analyte: Cl- 10000 ug/mL.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search